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Does Chorionic Villus Sampling Decrease Blood Flow to the Baby

Overview

Chorionic villus sampling (CVS) is a prenatal test in which a sample of chorionic villi is removed from the placenta for testing. The sample tin can be taken through the neck (transcervical) or the abdominal wall (transabdominal).

During pregnancy, the placenta provides oxygen and nutrients to the growing baby and removes waste product products from the babe's blood. The chorionic villi are wispy projections of placental tissue that share the infant'southward genetic makeup. The examination tin be done as early on as ten weeks of pregnancy.

Chorionic villus sampling tin reveal whether a infant has a chromosomal condition, such as Down syndrome, besides every bit other genetic atmospheric condition, such as cystic fibrosis. Although chorionic villus sampling can provide valuable data nearly your babe's health, it'due south important to empathize the risks — and be prepared for the results.

Chorionic villus sampling

During chorionic villus sampling, a thin tube is guided through the cervix (shown above) or a needle is inserted into the uterus to remove a sample of chorionic villus cells from the placenta. These cells incorporate a baby's genetic data.

Why information technology's done

Chorionic villus sampling tin provide information about your baby's genetic makeup. Generally, chorionic villus sampling is offered when the examination results might have a significant bear upon on the management of the pregnancy or your desire to proceed the pregnancy.

Chorionic villus sampling is usually done between weeks 11 and 14 of pregnancy — earlier than other prenatal diagnostic tests, such as amniocentesis.

Y'all might consider chorionic villus sampling if:

  • Yous had positive results from a prenatal screening exam. If the results of a screening exam — such as the commencement trimester screen or prenatal prison cell-free Deoxyribonucleic acid screening — are positive or worrisome, you lot might opt for chorionic villus sampling to ostend or dominion out a diagnosis.
  • Yous had a chromosomal condition in a previous pregnancy. If a previous pregnancy was affected by Down syndrome or some other chromosomal condition, this pregnancy may be at a slightly higher run a risk, likewise.
  • You lot're 35 or older. Babies built-in to women 35 and older take a college risk of chromosomal conditions, such as Down syndrome.
  • You have a family unit history of a specific genetic status, or you or your partner is a known carrier of a genetic status. In addition to identifying Down syndrome, chorionic villus sampling can be used to diagnose many other genetic conditions — including single gene disorders such every bit Tay-Sachs and cystic fibrosis.

Chorionic villus sampling can't discover certain birth defects, such equally neural tube defects. If neural tube defects are a concern, an ultrasound or genetic amniocentesis might be recommended instead.

Your health care provider might caution against transcervical chorionic villus sampling — which is washed through the vagina — if you have:

  • An active cervical or vaginal infection, such as herpes
  • Vaginal haemorrhage or spotting in the previous two weeks
  • An inaccessible placenta, due to a tilted uterus or noncancerous growths in your cervix or the lower part of your uterus

Rarely, your health care provider might caution against transabdominal chorionic villus sampling — which is washed through the abdominal wall — if:

  • Your uterus is titled backward and your placenta is located at the back of your uterus

Risks

Chorionic villus sampling carries various risks, including:

  • Miscarriage. The gamble of miscarriage subsequently chorionic villus sampling is estimated to exist 0.22 percentage.
  • Rh sensitization. Chorionic villus sampling might cause some of the baby'due south blood cells to enter your bloodstream. If yous have Rh negative blood and you lot haven't adult antibodies to Rh positive blood, you'll be given an injection of a blood product called Rh immune globulin after chorionic villus sampling.

    This will foreclose your body from producing Rh antibodies that tin can cross the placenta and harm the baby'south red blood cells. A claret test tin observe if you've begun to produce antibodies.

  • Infection. Very rarely, chorionic villus sampling might trigger a uterine infection.

Some older studies suggested that chorionic villus sampling might cause defects in a baby's fingers or toes. Withal, the take chances appears to exist a business but if the procedure is done earlier week 10 of pregnancy.

How you prepare

You might need to have a full bladder for chorionic villus sampling. Check with your provider well-nigh how much fluid y'all might need to drink, every bit well as any other pre-test preparation that might be necessary before your appointment.

Your health care provider will explain the process and ask yous to sign a consent course before the procedure begins. Consider asking someone to accompany you to the appointment for emotional back up or to drive y'all dwelling house afterwards.

What y'all can await

Chorionic villus sampling is unremarkably washed in an outpatient facility or the health care provider'south office.

During the process

Start, your health care provider will utilise ultrasound to verify your baby's gestational age and the position of the placenta. You'll lie on your back on an exam table with your abdomen exposed. Your health care provider will utilise a special gel to your abdomen, and and so use a small device known as an ultrasound transducer to show your baby's position on a monitor.

Next, your health care provider will use the ultrasound image as a guide and take the tissue sample from the placenta while y'all lie even so. This tin can be done through your cervix (transcervical) or your abdominal wall (transabdominal).

  • Transabdominal chorionic villus sampling. Subsequently cleansing your belly with an antiseptic, your health care provider volition insert a long, thin needle through your abdominal wall and into your uterus. You might discover a stinging sensation when the needle enters your skin, and you might feel cramping when the needle enters your uterus. The tissue sample from the placenta volition exist withdrawn into a syringe, and the needle will be removed.
  • Transcervical chorionic villus sampling. Afterwards cleansing your vagina and cervix with an antiseptic, your wellness care provider volition open your vagina with a speculum and insert a sparse, hollow tube through your cervix. When the catheter reaches the placenta, gentle suction will exist used to remove a modest tissue sample.

After the procedure

You might feel a pocket-size amount of vaginal bleeding immediately subsequently the process.

You can resume your normal activity level afterwards the procedure. However, yous might consider avoiding strenuous exercise and sexual activeness for a day.

Meanwhile, the tissue sample will be analyzed in a lab. Results might take a few days to a week or and so, depending on the complexity of the lab assay.

Contact your health care provider if yous have:

  • Fluid leaking from your vagina
  • Heavy bleeding
  • A fever
  • Uterine contractions

Results

Your wellness intendance provider or a genetic advisor will aid you lot understand your chorionic villus sampling results. Occasionally, test results are unclear and amniocentesis — another prenatal diagnostic examination — is needed to clarify the diagnosis.

With chorionic villus sampling, there's a rare chance of a false-positive examination — when the test is positive, only no disease exists. It's also important to retrieve that chorionic villus sampling can't identify all birth defects, including spina bifida and other neural tube defects.

If chorionic villus sampling indicates that your babe has a chromosomal or genetic condition that can't be treated, you might exist faced with wrenching decisions — such as whether to proceed the pregnancy. Seek support from your wellness care squad and your loved ones during this hard time.

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Source: https://middlesexhealth.org/learning-center/tests-and-procedures/chorionic-villus-sampling

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